Synthesis, Anti TB, Antioxidant, Antimicrobial Activity of some Isatin- 3hydrazone derivatives
نویسنده
چکیده
Some new isatin3hydrazone derivatives that are Isatin3(benzylidene)hydrazone, Isatin3-(methyl ethylide)hydrazone, isatin 3-(isoproplylidene)hydrazone have been synthesized from the reaction of isatin3-hydrazone and different aldehydes and ketones. Thestructure of synthesized compound is assigned on the basis of, IR, 1HNMR, 13CNMRdata. The anti microbial activity was done by disk diffusion method, all compound tested against three bacteria and two fungi.All compounds also screen for their antioxidant activity, among the synthesized compound, isatin3-(isoproplylidene)hydrazone exhibited excellent antioxidant activity and Antitubercular activity was done by disk diffusion method, result show that compound Isatin3(benzylidene)hydrazone is inactive against TB bacteria and Isatin3-(methyl ethylide)hydrazone, isatin 3(isoproplylidene)hydrazone show good activity against TB bacteria.
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